Police in London have arrested a 31-year-old man in connection with allegations of unauthorised trading which has cost Swiss banking group UBS an estimated $2bn (£1.3bn).
Kweku Adoboli, believed to work in the European equities division, was detained in the early hours of Thursday and remains in custody.
UBS shares fell 8% after it announced it was investigating rogue trades.
The Swiss bank said no customer accounts were affected.
A spokesman for City of London Police, which is responsible for the city's financial district, said: "We can confirm we arrested a 31-year-old man at 3:30am on suspicion of fraud by abuse of position."
In a letter to its 65,000 staff, UBS warned that the rogue trades could hit profits.
"The matter is still being investigated, but UBS's current estimate of the loss on the trades is in the range of $2bn," the bank said.
"It is possible that this could lead UBS to report a loss for the third quarter of 2011. No client positions were affected.
"While the news is distressing, it will not change the fundamental strength of our firm.
"We urge you to stay focused on your clients, who are counting on you to guide them through these uncertain times," the bank said.
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The Financial Times newspaper reported that Mr Adoboli worked as a director of Exchange Traded Funds in the equities department.
ETF's are a type of tradeable share that track movements in other indexes or commodities, and can be affected by short-term volatility in prices.
ZKB trading analyst Claude Zehnder said the news would damage confidence in UBS. "They obviously have a problem with risk management.
"With this, they are losing a lot of credit that they had regained with effort."
UBS was rescued by the Swiss state in 2008, following huge losses on toxic assets held by its investment bank.
It then became embroiled in a serious tax evasion dispute with US authorities and was forced to hand over 300 client names and pay a $780m fine. There was then a second case in which it agreed to hand over data on 4,450 American clients.
UBS declined to say in which department, or country, the rogue trader operated. However, there is already speculation that the losses may have occurred in foreign exchange trades.